Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...

Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing ...

The cytoskeleton is far more than a static scaffold—it’s a dynamic, adaptable network that shapes cells, moves cargo, and drives vital processes. From swirling cytoplasmic flows to microtubule ...

Tiny things matter – for instance, one amino acid can completely alter the architecture of the cell. Researchers at the Universities of Göttingen and Warwick investigated the structure and mechanics ...

Actin filaments are dynamic protein-fibers in the cell built from single actin proteins. Many cellular functions, including cell movement, are regulated by constant filament assembly and disassembly.

Cells constantly search for physical cues that guide their behavior yet respond biochemically. How a cell converts mechanical ...