Aldehydes, ketones and carboxylic acids are the compounds containing carbon-oxygen double bond (>C=O) called carbonyl group. The carbon and oxygen of the carbonyl group are sp 2 hybridised and the ...
We describe a method for modifying proteins site-specifically using a chemoenzymatic bioconjugation approach. Formylglycine generating enzyme (FGE) recognizes a pentapeptide consensus sequence, CxPxR, ...