The detrimental effects caused by substances or environmental changes on cell health are described as cytotoxicity. When cells are exposed to a cytotoxic stimulus, their metabolic activity may be ...

Assessment of circulating tumor cell (CTC) patterns among disease-free breast cancer patients vaccinated with a preventive HER2/neu E75-peptide vaccine No significant financial relationships to ...

Background: Quantitative structure-activity relationship (QSAR) models have become popular tools to help identify promising lead compounds in anticancer drug development. Few QSAR studies have ...

BCR-ABL monitoring in imatinib-treated patients with chronic myelogenous leukemia. Background: CD74 (DR-associated invariant chain) is expressed alone or with DR in a wide range of hematologic cancers ...

The reporter bioassay, used to evaluate ADCC activity of therapeutic antibodies, complements the classical ADCC assay. Antibody-dependent cell-mediated cytotoxicity (ADCC) is an important mechanism of ...