Building on an in vivo genetic screen in mice to identify host regulators of cancer metastasis, 4 Yang et al. focused on ARHGEF1, which is 1 of 15 genes whose disruption in host tissues decreases the ...

Dr. Vikram Gorantla explains to CURE that staying healthy and managing side effects helps patients with brain metastases remain on therapy. Dr. Vikram C. Gorantla, a medical oncologist at University ...

Triple-negative breast cancer—the most aggressive breast cancer subtype—has a high propensity for brain metastases, with ...

Dr. Konduri provides an overview of the current frontline treatment landscape for metastatic EGFR-positive NSCLC. Targeted therapies are the cornerstone, including the tyrosine kinase inhibitor ...

Researchers at the University of Chicago have shed light on the role of tumor-promoting factors induced by radiotherapy and their potential impact on future therapeutic strategies. The article, ...

Efficacy and safety of nimotuzumab plus AG regimen as conversion therapy for locally advanced pancreatic cancer: A prospective, single-arm study. This is an ASCO Meeting Abstract from the 2025 ASCO ...

Cancer metastasis, the spread of cancer to organs, is a major cause of cancer-related deaths. Once cancer spreads to multiple organs, conventional treatments like surgery, radiation, and chemotherapy ...

Preoperative radiation therapy targeting brain metastases can activate immune pathways that typically are suppressed, results ...

The primary end points were FISST and local control (LC) rates of lesions that received SBRT. The secondary end point was overall survival (OS) after SBRT. To calculate FISST, event was defined as the ...

Scientists have identified a molecular switch that may help explain how colorectal cancer becomes deadly. When levels of a ...