Prof. Heiko Lickert is the director of the Institute of Diabetes and Regeneration Research at Helmholtz Munich, professor at the Technical University of Munich (TUM), and member of the German Center ...

Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The blocking of inceptor function leads to an increased sensitisation of the insulin signaling pathway in ...

Hormones are chemical messages that send signals throughout the body. They work slowly and affect body growth, development, metabolism, sexual function, mood, and other functions. Many medications are ...

UB researchers—the first to identify the anti-inflammatory and cardioprotective properties of insulin—now have discovered one pathway through which the hormone produces this effect. Insulin appears to ...

Developing resistance to insulin is a key step on the road to diabetes, making insulin resistance a target for treating metabolic dysfunction. Insulin orchestrates blood glucose levels by signaling ...

Three years ago, the inceptor protein was discovered and its role as an inhibitor of the insulin signaling pathway was described. Inceptor and the insulin receptor are located on the surface of beta ...

A new study published in the International Journal of Molecular Sciences discusses the impact of herpes, influenza, hepatitis, human immunodeficiency virus (HIV), the severe acute respiratory syndrome ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

A new study uncovers how endothelial cells contribute to insulin resistance in obesity-associated diabetes, highlighting adrenomedullin as a potential therapeutic target. Study: Endothelial insulin ...