Against this backdrop, a team led by Professor Zhang Han and Associate Professor Chen Zhi from Shenzhen University in China , has demonstrated an innovative approach that combines DNA origami, CRISPR ...

Liquid biopsy is increasingly recognized as a promising tool for cancer detection and treatment monitoring, yet its effectiveness is often limited by the extremely low levels of tumor-derived DNA ...

A minor alteration in a single gene of the human body can be a major contributor to the development of a wide spectrum of diseases ranging from cystic fibrosis to cancer. With the Human Genome Project ...

Researchers have developed a novel way of detecting brain cancer, using nanowires to ‘catch-and-release’ DNA in urine, enabling them to detect mutations that signify the presence of a brain tumor.

The model suggests that negative KRAS findings are believable when the maximum of APC and TP53 frequencies is at least 8% (corresponding posterior probability of false negative <5%). Validation ...

A new platform for studying mtDNA mutations implicated in human disease could help accelerate treatments for mitochondrial ...

Using the LightCycler 480 System for Discovery and Analysis of Genetic Variation LightCycler® Real-time PCR Systems from Roche (www.roche.com) are efficient platforms for genetic variation research.

One reason that researchers do not always find specific DNA sequence variations in genes associated with muscular dystrophy (MD) is that they lack a reliable and cost-effective assay to detect point ...

New research suggests that autoimmune diseases may be driven by DNA mutations in immune cells that remove the natural brakes ...