As the number of antibiotic-resistant infections continues to rise, scientists are looking to bacteriophages (“phages”), viruses that infect bacteria, as an approach to tackling antibiotic resistance.

Researchers at the University of Southampton have used advanced imaging techniques to uncover how bacteria use a mechanism called Kiwa to defend themselves against phage viruses. Phages are seen as a ...

Mammalian cells initiate antiviral signaling when cyclic GMP-AMP synthase (cGAS) detects cytoplasmic DNA and synthesizes 2',3'-cyclic GMP-AMP (2',3'-cGAMP), which activates stimulator of interferon ...

From antibiotics to antibacterial wipes, humans have developed ways to battle the threats microbes pose to our health. But bacteria are also contending with their own biological threats. These threats ...

As antibacterial resistance continues to render obsolete the use of some antibiotics, some have turned to bacteria-killing viruses to treat acute infections as well as some chronic illnesses. Graham ...

Bacteria have evolved sophisticated antiphage systems that halt phage replication upon detecting specific phage triggers. Identifying phage triggers is crucial to our understanding of immune ...

What if the Trojan horse had been pulled to pieces, revealing the ruse and fending off the invasion, just as it entered the gates of Troy? That's an apt description of a newly characterized bacterial ...

As the globe faces a rise in antibiotic-resistant bacteria – making traditional antibiotics ineffective – specific viruses could offer a solution. Viruses called bacteriophages, or phages, target ...