Clinical genome sequencing now delivers genetic diagnoses for about 1 in 4 suspected rare disease patients, guiding targeted ...

Metagenomics relies on the use of software programs called assemblers, which can reconstruct tens of thousands of individual ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest questions. Consisting of amino acids strung together into peptide chains, these ...

Advances in DNA sequencing technology help forensic biologists identify suspects where traditional DNA profiling has failed, ...

Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how ...

Sanger sequencing is the unsung workhorse of molecular biology, one whose value has long been undermined by the tedious nature of processing its data. Converting files of raw sequencing data into a ...

Long read sequencing improves detection of structural variants in paediatric leukaemia, identifying missed gene fusions and aiding diagnosis.

A team at Rice University has built a lab platform that can map the activity of more than 10 million protein variants in a ...

Panel A shows dereplicated reads from wastewater virome sequencing assigned to H5N1 from all samples with a validated H5N1 signal aligned to a recently collected H5N1 2.3.4.4b reference sequence ...

Single-cell sequencing is useful for a number of applications. For example, it can reveal cellular heterogeneity inside complex tissues, such as tumors. It can also provide information about how ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...