Determining the presence of a protein in non-tumor cells within the cancer microenvironment could be one of the keys to ...

Despite major advances in targeted therapies, immunotherapies, and combination regimens, therapy resistance remains a central barrier to durable cancer ...

Among the presentations included in the Top Abstracts category at the recently inaugurated Annual Congress of the European Association for Cancer Research (EACR) in Lisbon, it is worth highlighting ...

Existing oncology therapeutics are either so specific they can target only part of a tumor, or so generalized they kill healthy tissue. A new “Tumor Activated Therapy™” in development at the small ...

The inflammatory tumor microenvironment (TME) is a complex network of cancer, immune, and stromal cells interacting through cytokines and growth factors to drive tumor growth, angiogenesis, and immune ...

Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be harnessed for cancer therapy. Given that more than 95% of pancreatic ductal ...

Intratumoral microbiota—the microbial populations residing within solid tumors—have emerged as pivotal components of the tumor microenvironment (TME), influencing tumor initiation, progression, and ...

When cancer subtypes were examined, the analysis revealed that phototherapy was linked to a 40% increased odds of blood cancers. More modest associations were observed for solid organ cancers and ...

Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor ...

Photothermal therapy (PTT), in which suitable photosensitive agents or nanoparticles are introduced to malignant tissues and then heated by an incident laser, is a valuable tool in clinical treatment ...