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A new comprehensive review is shedding light on the expanding role of focal adhesion kinase (FAK) in cancer biology and its potential as a ...
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Nanoparticle therapy targets lung tumors and cancer-related muscle loss
A team at Oregon State University has engineered lipid nanoparticles that deliver messenger RNA to lung tumors while ...
A new review links three forces shaping osteoarthritis: mechanical stress, integrin signaling, and integrin endocytosis. The authors argue that integrin trafficking can reprogram where and how long ...
Russian intelligence-linked hackers are targeting users of popular messaging apps like Signal, gaining access to private messages and impersonating victims in a sweeping global campaign, according to ...
Atherosclerosis represents a chronic inflammatory disease characterized by the accumulation of lipid-laden macrophage foam cells within arterial walls, serving as the underlying pathological basis for ...
Background: Mfge8 is an integrin ligand and a major exosome (EV) protein known to mediate inflammation and atherosclerosis in type 2 diabetes mellitus (T2DM) in animal research. The pathophysiological ...
This research explores how the mobility of a key immune ligand, intercellular adhesion molecule 1 (ICAM1), influences T cell activation. T cells have a receptor that specifically binds to ICAM1, ...
ABSTRACT: Objective: To investigate the expression characteristics, clinical significance, and immune regulatory mechanisms of colony stimulating factor receptor α (CSF2RA) in gastric cancer (GC) ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Nanoscale organization of integrin-mediated receptor crosstalk is crucial for ...
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