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🧠 The first immunocompetent H3 G34R pediatric brain tumor model shows a decisive outcome: dendritic cell vaccination with whole tumor lysate + anti–PD-1 achieves durable survival, while 100% of controls die.The G34R mutation itself is not a demonstrated neoantigen.The dendritic cells identified targets bioinformatics could not predict.🔬 Whole lysate. Competent instructor. The immune system executes.📊 In the DCVax-L Phase III trial, a single product yielded:25,109 MHC-I peptides12,940 MHC-II p
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